Weight Loss and Increased Risk of Kidney Disease for Type 1 Diabetes Patients
Yo-yo dieting, or body-weight cycling, poses significant health risks for individuals, particularly those with type 1 diabetes. New research published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism highlights a potential link between weight fluctuations and kidney disease in this population.
The six-year study analyzed body-weight data from more than 1,400 participants in the Diabetes Control and Complications Trial (DCCT) and the Epidemiology of Diabetes Interventions and Complications (EDIC) study. Researchers found that individuals who experienced more significant weight fluctuations had a 40% decline in their estimated glomerular filtration rate (eGFR), a measure of kidney function.
Additionally, those with greater weight fluctuations were more likely to experience moderately to severely increased albuminuria, a condition marked by high levels of the protein albumin in the urine, often associated with kidney disease. The researchers also confirmed similar findings of kidney disease in all indices examined, signifying a potential connection between body-weight cycling and increased renal risks.
Lead author Marion Camoin, M.D., noted that this study is the first to identify a connection between yo-yo dieting and kidney events in individuals with type 1 diabetes. However, the exact mechanisms linking weight cycling to increased renal risks are not yet fully understood. Insulin therapy used to treat type 1 diabetes is a potential contributing factor, while others believe that body-weight cycling may cause added strain on the heart and contribute to kidney and vascular damage.
Weight management is vital for reducing the risk of kidney disease in individuals with type 1 diabetes. This involves balancing diet, exercise, and effective blood glucose management. Experts suggest that strategies aimed at weight reduction should focus on promoting long-term weight maintenance for better health outcomes.
Weight gain in individuals with type 1 diabetes can result from various factors, such as taking too much insulin, treating multiple hypos, inactivity due to fear of highs and lows, and overconsumption of high-calorie, low-carb foods. Effective management of weight is essential for maintaining stable blood glucose levels and reducing the risk of complications, including kidney disease.
Reference(s):- Yo-yo dieting may significantly increase kidney disease risk in people with type 1 diabetes - EurekAlert!- What Happens to Your Body When You Yo-Yo Diet - WebMD- Consequences of Weight Cycling: An Increase in Disease Risk? - NIH- The Long-Term Effects Of Yo-Yo Dieting - Forbes
- The study in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism suggests a potential link between yo-yo dieting, weight fluctuations, and chronic kidney disease, especially in individuals with type 1 diabetes.
- Weight cycling, or yo-yo dieting, may cause a 40% decline in estimated glomerular filtration rate (eGFR) and an increased likelihood of moderately to severely increased albuminuria, conditions often associated with kidney disease.
- To reduce the risk of kidney disease in individuals with type 1 diabetes, it is crucial to focus on weight management strategies that promote long-term weight maintenance, involving balanced nutrition, regular exercise, and effective blood glucose management.
