Title: Understanding Contrave for Weight Loss: Dosage and Considerations
Contrave, a brand-name medication, has gained FDA approval for aiding in weight loss and weight management for certain adults. Prescribed along with exercise and a reduced-calorie diet, Contrave is beneficial for individuals battling obesity, overweight, and associated health issues such as type 2 diabetes, high cholesterol, and high blood pressure.
The medication is available as extended-release oral tablets, boasting two active ingredients: naltrexone and bupropion. Naltrexone belongs to the opioid antagonist drug class, while bupropion is an antidepressant from the antidepressant class. These components work synergistically to support weight management.
As of now, there isn't a generic version of Contrave, making it exclusive to the brand.
Week of treatment
Dosage Details
Daily dosage
Typical Contrave dosages include:
Week 1
Contrave is available in extended-release (ER) tablets, allowing the drug to gradually release into your system over time after ingestion. You will swallow the tablet without chewing, crushing, or breaking it apart.
morning: one tabletevening: none
Strengths
Each tablet consists of 8mg naltrexone and 90mg bupropion.
Week 2
Prescription Details
morning: one tabletevening: one tablet
Initially, your doctor may prescribe a low dosage, which will be gradually increased over time based on your body’s response to the medication. This will eventually reach the optimal dosage for your needs.
Increasing Dosages
Week 3
Doctors often recommend increasing your dosage during the first 4 weeks of treatment. After this period, you typically continue with the same dosage. The most common dosage recommendations are outlined below:
morning: two tabletsevening: one tablet
| Week of treatment | Daily dosage || --- | --- || Week 1 | Morning: one tablet || Week 2 | Morning: one tablet, Evening: one tablet || Week 3 | Morning: two tablets, Evening: one tablet || Week 4 and afterward | Morning: two tablets, Evening: two tablets |
Week 4 and after
Enrichment Insights
morning: two tabletsevening: two tablets
If you're considering alternative medications for weight loss, you may want to explore options like:
- Phentermine: An appetite suppressant that works by decreasing hunger and increasing feelings of fullness. It is available in tablet, capsule, extended-release, or disintegrating tablet form and is typically taken once daily before or after breakfast.
- Qsymia (Phentermine/Topiramate): A combination medication that pairs phentermine, an appetite suppressant, with topiramate, a drug originally used to treat seizures and migraines. It helps to suppress appetite and promote feelings of fullness, contributing to weight loss. Qsymia is available orally once daily, with a healthy diet and regular exercise regimen.
- Xenical (Orlistat): While not a direct generic alternative to Contrave, Xenical is an oral medication that aids weight loss by preventing fat absorption within the body. It should be taken three times daily within an hour of a meal containing fat.
- Off-label medications: Medications like Metformin, Topiramate, and Bupropion may be considered off-label options for weight management by healthcare professionals. However, it's essential to consult your doctor regarding these alternatives.
The decision to prescribe Contrave for managing obesity and related health issues like type 2 diabetes and high blood pressure lies with healthcare deciders who consider the patient's overall health and response to the medication. Patients should be cautious when considering alternative weight loss drugs, such as Phentermine and Xenical, as they contain different active ingredients and have unique dosage guidelines, potentially interacting with other drugs or affecting one's health.
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