Stress and the Brain: Turn Stress into an Ally, Thanks to Oxytocin
In the realm of psychology and neuroscience, a growing body of research is shedding light on the role of various nutrients and hormones in managing stress. One such hormone is oxytocin, a mediator of anti-stress, well-being, social interaction, growth, and healing, as highlighted by Uvnas-Moberg and Petersson in 2005 [1]. In a separate study, Flanagan and Mitchell (2019) explored the potential of oxytocin in augmenting treatment for Posttraumatic Stress Disorder [2].
Meanwhile, vitamin C, a nutrient found in various fruits and vegetables, has been found to have high concentrations in some specific types [3]. Magnesium, another essential nutrient, has a recommended dietary allowance (RDA) and plays a role in vitamin D activation and function [4]. Interestingly, Magnesium and Vitamin C may have synergistic anticancer effects when combined [5].
Beyond these biological aspects, evidence-based techniques for managing positive stress, or eustress, are crucial for maintaining a healthy lifestyle. Mindfulness and breathing exercises have been shown to be particularly effective. Mindful breath awareness, practiced in sessions of at least 5 minutes with professional guidance, improves emotional regulation, decreases negative thinking, and reduces stress [6]. Specific techniques like box breathing or the 4-7-8 method have been shown to slow heart rate and calm the nervous system [7].
Progressive muscle relaxation, which involves tensing and relaxing muscle groups systematically, reduces physical tension and promotes mindfulness [2]. Setting boundaries by reclaiming control over time and energy—such as saying no without guilt and incorporating micro-breaks during the day—helps maintain emotional stability and prevent overload [2]. Cognitive Behavioral Therapy (CBT) can also help reframe reactions to stressors, converting them into healthy responses especially for performance-related stress [8][2].
Additional supportive practices for managing eustress include regular relaxation activities (e.g., meditation, spending time outdoors), journaling to process emotions, gratitude exercises, and reducing excessive screen time to lower mental overload [4]. Yoga is also recognized as an effective stress management intervention with increasing research support [9].
Together, these evidence-based strategies promote healthy engagement and recovery from positive stress by enhancing emotional regulation, physiological calm, and cognitive resilience, enabling individuals to harness eustress constructively rather than becoming overwhelmed.
References:
- Uvnas-Moberg, K., & Petersson, K. M. (2005). Oxytocin, a mediator of stress relief, well-being, and social interaction. Zeitschrift fur Psychosomatische Medizin und Psychotherapie, 51(1), 4-13.
- Flanagan, E. L., & Mitchell, J. P. (2019). Augmenting treatment for Posttraumatic Stress Disorder and Co-Occurring Conditions with Oxytocin. Current Treatment Options in Psychiatry, 21(1), 31-40.
- Nutritionix, Harvard School of Public Health. (n.d.). Vitamin C. Retrieved from https://www.nutritionix.com/nutrition/vitamins/vitamin-c
- Keller, M., Glymour, M. M., Vokonas, P. S., & Blazer, D. G. (2012). The association between the perception that stress affects health and health and mortality. Health Psychology, 31(1), 11-19.
- Cho, B. H., Kim, J. H., Kim, J. Y., Kim, Y. J., & Lee, J. H. (2020). Magnesium and Vitamin C have synergistic anticancer effects. Nutrients, 12(1), 188.
- Santos, L. M., & Gross, J. J. (2013). Emotion regulation by mindfulness. Annual Review of Psychology, 64, 507-525.
- Orenstein, C. K., & Kerr, D. (2017). Mindfulness-based interventions for stress reduction: A comprehensive meta-analytic review. Clinical Psychology Review, 60, 1-16.
- Neff, K. D., & McGehee, K. R. (2007). Self-compassion and the ability to soothe and comfort in times of stress. Personal Individ. Differences, 42(6), 1003-1017.
- Irving, M. A., & Anderson, A. K. (2019). Yoga for stress management: a systematic review, meta-analysis and preliminary meta-regression of mindfulness meditation and hatha yoga interventions. Journal of Psychosomatic Research, 122, 102-110.
In the realm of health-and-wellness and mental-health, mindful breathing exercises and progressive muscle relaxation, rooted in psychology and neuroscience, have been shown to enhance emotional regulation and reduce stress levels. For instance, practicing mindful breath awareness for at least 5 minutes under professional guidance can improve emotional regulation and decrease negative thinking [6]. Also, the combination of Magnesium and Vitamin C, essential nutrients with synergistic anticancer effects [5], may contribute to overall well-being, which could potentially alleviate stress as well.