Discovered: Microplastics inside human brains, impacts yet to be determined by researchers
In recent years, microplastics have been discovered in various aspects of our lives, from the air we breathe to the food we eat. A concerning development is the detection of microplastics in human organs, including the brain.
A study published in the prestigious journal Science Advances in January 2025 revealed the presence of microplastics in mouse brains, providing a glimpse into the potential impact on human health. This discovery was preceded by research indicating that microplastics can cross the blood-brain barrier, a crucial biological barrier that protects the brain from harmful substances.
Current research suggests that microplastics have indeed been detected in human brains and other organs. A study using advanced imaging techniques demonstrated that microplastics in the bloodstream can be engulfed by immune cells, which then get trapped in tiny brain blood vessels, potentially causing neurological impairments[1].
The concentrations of microplastics in human brain tissue have reportedly increased by about 50% from 2016 to 2024, with the average adult brain containing around seven grams of microplastics—the weight of a plastic spoon[5]. These particles are capable of crossing biological barriers such as the blood-brain barrier, likely in the form of smaller nanoplastics[2].
Laboratory studies show that microplastics can cause oxidative stress, inflammation, and cellular damage, which are associated with risks for neurological and other systemic diseases[2][4]. Moreover, microplastics act as vessels for pathogens and toxic chemicals, potentially increasing disease spread and causing endocrine disruption, reproductive problems, growth and cognitive impairments, and other serious health issues[4].
While much of the direct evidence of harm is currently from animal models or in vitro studies, human studies are emerging. However, more research is needed to fully understand the clinical implications and exposure thresholds for microplastic-induced brain injury and broader health effects[1][2][4][5].
The potential threat posed by microplastics has led many health experts to cite the precautionary principle, urging action to mitigate potential harm. The increasing ubiquity of microplastics is a key issue in efforts to create a plastic pollution treaty.
However, the World Health Organization (WHO) has stated that the evidence is insufficient to determine the risks to human health from microplastics. This highlights the need for continued research and the importance of policy decisions that prioritise caution and precaution.
References:
[1] Science Advances, 2025 [2] Environmental Science & Technology, 2023 [3] The Lancet, 2024 [4] Environmental Health Perspectives, 2022 [5] Nature Medicine, 2024
- The world of health and wellness is increasingly focused on the potential impact of microplastics, as research indicates that these tiny pollutants have been detected in human brains and other organs, with concentrations reportedly increasing.
- There is growing concern about the role of microplastics in environmental science, as these pollutants are known to act as vessels for pathogens and toxic chemicals, potentially causing diseases and health issues such as oxidative stress, inflammation, and cellular damage.
- In a bid to address the potentially serious health implications of microplastics, health experts are advocating for the precautionary principle in policy decisions, emphasizing the need for continued research and measures to mitigate potential harm, particularly in arts and cultural activities that may contribute to plastic pollution.
