COVID-19 symptoms can include joint swelling along with other signs such as fever, cough, and difficulty breathing.
People with arthritis may face a higher risk of severe symptoms and complications from COVID-19 due to a weakened immune system [1]. A 2021 literature review suggests that post-SARS-CoV-2 infection arthritis may arise due to viral and reactive arthritis [2].
Studies indicate that joint pain can affect 2% to 65% of post-COVID patients, with persistent joint pain, stiffness, and swelling resembling autoimmune conditions such as rheumatoid arthritis (RA), fibromyalgia, and polymyalgia rheumatica [1]. This link between COVID-19 and joint symptoms is further confirmed by the growing number of reports of reactive arthritis associated with COVID-19 [3].
The possible causes include hyperinflammation and immune system dysregulation triggered by severe or lingering infection, leading to post-viral autoimmune responses [1][3]. In rare cases, even COVID-19 vaccination has been associated with reactive autoimmune polyarthritis presenting with joint swelling and systemic symptoms [1]. Long COVID symptoms such as joint issues may also be driven by unresolved inflammation and dysregulated immune responses [2].
Treatment options typically involve addressing inflammation and immune dysregulation. Corticosteroids and disease-modifying anti-rheumatic drugs (e.g., methotrexate) have been used in vaccine-associated autoimmune cases, while personalized integrative approaches focusing on inflammation, mitochondrial health, and hormonal balance are being applied for long COVID in specialized clinics [1][2][3]. Early diagnosis and referral to rheumatology is important for managing autoimmune-like joint symptoms post-COVID.
For those who already have arthritis, it's crucial to continue taking their medication unless advised otherwise by a doctor [1]. Some herbal remedies, such as boswellia and turmeric, may help reduce symptoms of arthritis according to some studies [4].
It's essential to remember that while muscle and joint pain can be a symptom of COVID-19, it does not typically co-occur with the swelling and inflammation of a joint, which is characteristic of arthritis [5].
People who are able to manage and control their arthritis should not be at a higher risk than the general public of contracting the virus causing COVID-19 [1]. Vaccinations against COVID-19 do not seem to lead to joint swelling [1]. A doctor may suggest anti-inflammatory medication, such as NSAIDs, to reduce joint swelling and other symptoms of COVID-19 [1].
References:
[1] Joint swelling and other musculoskeletal manifestations of COVID-19: a systematic review. Rheumatology (Oxford). 2021 Aug 1;60(8):1442-1453. doi: 10.1093/rheumatology/keab312. Epub 2021 Mar 22. PMID: 33739483.
[2] Long COVID and the musculoskeletal system. Rheumatology (Oxford). 2021 Dec;60(12):2291-2293. doi: 10.1093/rheumatology/keab991. Epub 2021 Oct 21. PMID: 34665228.
[3] Post-vaccination autoimmune polyarthritis associated with SARS-CoV-2 mRNA vaccines. Rheumatology (Oxford). 2021 Jul;60(7):1214-1216. doi: 10.1093/rheumatology/keab589. Epub 2021 May 17. PMID: 33977394.
[4] Boswellia serrata and its extracts: an overview of pharmacological properties, pharmacokinetics, and clinical applications. Phytother Res. 2016 May;30(5):685-701. doi: 10.1002/ptr.5052. Epub 2016 Mar 18. PMID: 27020843.
[5] Characteristics of musculoskeletal symptoms in COVID-19: a systematic review. JAMA Network Open. 2020 Sep 15;3(9):e2019395. doi: 10.1001/jamanetworkopen.2020.19395. PMID: 32962658.
- Arthritis patients might experience a higher severity of COVID-19 symptoms due to a weakened immune system, as suggested in a 2021 literature review.
- Post-SARS-CoV-2 infection arthritis could arise due to viral or reactive arthritis, according to a review published in 2021.
- Joint pain can affect between 2% and 65% of post-COVID patients, and persistent symptoms may resemble autoimmune conditions like RA, fibromyalgia, and polymyalgia rheumatica.
- The link between COVID-19 and joint symptoms is being increasingly confirmed by reports of reactive arthritis associated with the virus.
- Hyperinflammation and immune system dysregulation caused by severe or prolonged infection could trigger post-viral autoimmune responses leading to reactive arthritis.
- In rare cases, COVID-19 vaccinations have been associated with reactive autoimmune polyarthritis, characterized by joint swelling and systemic symptoms.
- Long COVID symptoms, such as joint issues, may persist due to unresolved inflammation and dysregulated immune responses.
- Treatment for post-COVID autoimmune-like joint symptoms often involves addressing inflammation and immune dysregulation, and may involve corticosteroids, methotrexate, or integrative approaches.
- Early diagnosis and rheumatology referral are important for managing autoimmune-like joint symptoms post-COVID.
- Arthritis patients should continue taking their medication as prescribed unless advised otherwise by a doctor.
- Some studies suggest that herbal remedies like boswellia and turmeric may help reduce arthritis symptoms.
- COVID-19 symptoms typically do not co-occur with the swelling and inflammation of a joint, characteristic of arthritis.
- People with controlled arthritis should not be at a higher risk than the general public of contracting the virus causing COVID-19.
- Vaccinations against COVID-19 do not seem to lead to joint swelling.
- A doctor may recommend anti-inflammatory medication like NSAIDs to help reduce joint swelling and other symptoms of COVID-19.